tailieunhanh - Frequent occurrence of tetrodotoxin in the marine gastropod Nassarius glans causing a food poisoning in Khanh Hoa province, Vietnam in 2020

The result pointed out that only 5 g of soft tissue from N. glans (equivalent to 2–3 specimens) containing maximum toxicity detected in the present study may cause human death if consumed. Fhe first time, this study identified TTXs in the gastropods as a causative toxin in the poisoning in Vietnam. Moreover, of studied specimens with high toxicity higher than 100 MU/g, including , showing extremely high toxicity (> 1,000 MU/g). The results suggested that this gastropod is quite dangerous for human consumption and should be alerted to public awareness. | Vietnam Journal of Marine Science and Technology 2023 23 2 203 208 Vietnam Academy of Science and Technology Vietnam Journal of Marine Science and Technology journal homepage jmst Frequent occurrence of tetrodotoxin in the marine gastropod Nassarius glans causing a food poisoning in Khanh Hoa province Vietnam in 2020 Dao Viet Ha Le Ho Khanh Hy Pham Xuan Ky Bui Quang Nghi Nguyen Phuong Anh Phan Bao Vy Doan Thi Thiet Institute of Oceanography VAST Vietnam Received 14 Febuary 2023 Accepted 26 April 2023 ABSTRACT A fatal neurotoxic poisoning case happened in Khanh Hoa province in 2020 after eating a certain number of marine gastropods later identified as Nassarius glans one of the common marine gastropods in Vietnam. As the remaining causative food in the incident 62 specimens were collected to examine tetrodotoxin toxicity individual variation and frequency of toxic specimens by using HILIC MS-MS analysis. 100 of studied specimens exhibited toxicity 556 821 MU g beyond the regulatory level of consumption 10 MU g for puffer fish recommended in Japan and extensive variation 18 4 046 MU g . The result pointed out that only 5 g of soft tissue from N. glans equivalent to 2 3 specimens containing maximum toxicity detected in the present study may cause human death if consumed. Fhe first time this study identified TTXs in the gastropods as a causative toxin in the poisoning in Vietnam. Moreover of studied specimens with high toxicity higher than 100 MU g including showing extremely high toxicity gt 1 000 MU g . The results suggested that this gastropod is quite dangerous for human consumption and should be alerted to public awareness. Keywords HILIC MS-MS Nassarius glans poisoning tetrodotoxin Vietnam. Corresponding author at Institute of Oceanography 01 Cau Da St. Nha Trang city 650000 Khanh Hoa Vietnam. E-mail addresses daovietha69@ https 1859-3097 18080 ISSN 1859-3097 e-ISSN 2815-5904 2023 Vietnam Academy of Science

• Địa Lý
• Nassarius glans
• Specimens exhibited toxicity
• TTX bearing species
• General clinic
• Toxicity individual
• Tạp chí Khoa học và Công nghệ biển
• Individual variation of toxicity
• Three vietnamese toxic marine puffer species
• High Performance Liquid Chromatography
• The toxicity of various organs